High transferases are not necessarily a sign of liver disease. Transferases include glutamyl transferase (GGT), alanine aminotransferase (ALT) and aspartate aminotransferase (AST), all three of which are present in human liver cells. When liver cells are damaged, all three enter the bloodstream and can lead to elevated transferases in the serum, so high transferases may be caused by liver disease. However, these three transferases also exist in the human biliary tract, pancreas, heart and other parts of the body, although not as much as in the liver, but they can also cause abnormal values of transferases, so high transferases are not necessarily liver disease, and need to be combined with other clinical symptoms and examination results to be judged by professional doctors.1. Liver diseases: acute and chronic viral hepatitis, alcoholic hepatitis, cirrhosis and other liver diseases can usually cause liver cells If patients have pain in the liver area (right upper abdomen), jaundice, diarrhea, abdominal distension and other manifestations, blood tests suggest high transferase, low serum protein, ultrasound and other tests suggest abnormal liver size and texture, it may indicate liver disease; 2, biliary tract diseases: for example, gallstones, bile duct tumors, etc. can also lead to elevated glutamyl transferase in the blood, and the patient’s performance is similar to that of liver disease. It is recommended that imaging examinations be performed to determine, such as hepatobiliary ultrasound or magnetic resonance bile duct water imaging, etc. If there are thickening, dilatation, stones and polyps in the biliary tract, it is generally considered that the transferase is high due to biliary tract diseases; 3, pancreatic diseases: pancreatitis, pancreatic tumors and other pancreatic diseases can also lead to mildly elevated transferase, but patients generally show pain in the left upper abdomen or middle and upper abdomen, and before the symptoms appear, there can be It is recommended to perform imaging examinations to determine, such as pancreatic ultrasound or CT, if it indicates enlargement of the pancreas or exudation around the pancreas, it may be caused by pancreatic diseases with high transferase; 4. heart diseases: when heart diseases such as acute heart infarction, heart failure and myocarditis develop, it may also cause myocardial cell necrosis, resulting in transferase into the blood and elevated transferase, which is usually accompanied by chest pain, palpitations, shortness of breath and other symptoms. Patients usually have chest pain, palpitations, shortness of breath and other symptoms, and need to be judged based on ECG, ECG ultrasound and other tests. In addition, physiological reasons such as strenuous exercise, alcohol consumption, and liver damage caused by drug-related liver injury or abuse of health care products may also cause different degrees of transferase elevation. Therefore, a high index of transferase alone is not enough to determine whether it is liver disease, and a systematic and comprehensive examination with a clinician is needed.