As the first line of treatment of strong column – non-steroidal anti-inflammatory drugs include: aspirin, indomethacin, ibuprofen and its extended-release capsules, fotarine, Dafen, loxoprofen sodium tablets, nimesulide, meloxicam, clonoxicam, celecoxib (Celebrex), erexab, etoricoxib, etc., but can only be used one by one, must not be used in combination, which can only increase the side effects of this class of drugs, generally If the effect is poor or ineffective after 3 weeks of application, it is necessary to replace another one. During the medication period, blood, urine routine and liver and kidney function should be reviewed regularly.