Kawasaki disease, also known as cutaneous mucosal lymph node syndrome, is an acute febrile rash disease first reported by Dr. Tomisaku Kawasaki in Japan and named after him. The onset of the disease is a systemic vasculitis involving large and small blood vessels throughout the body, the most sensitive being the coronary arteries that supply blood to the heart. Vasculitis can cause damage to the elastic fibers of the blood vessel walls, dilatation of the blood vessels, and even the formation of coronary aneurysms, which are very serious complications. It is more frequent in Asians and occurs mostly in infants and children under 5 years of age, with a peak incidence at 6 to 11 months of age, and in small infants as young as 1 month or so, and in children over 5 years of age. The incidence rate is higher in boys than in girls (1.35-1.5:1), with a recurrence rate of 1%-3%, and the disease occurs in all seasons, slightly more in China in spring and summer. The cause of Kawasaki disease is still unknown. It is considered to be related to the immune disorder of the body, and may also be related to infection, genetic susceptibility, and superantigenic immune response. If a child is suspected of having Kawasaki disease, the doctor will hospitalize the child and conduct a detailed examination and observation of changes in the condition. Some of the signs do not persist, or even pass away, and if they are not observed in time, they may affect the doctor’s diagnosis of the disease; relevant blood tests and imaging examinations are also performed. Such as cardiac ultrasound, abdominal ultrasound, lymph node ultrasound, blood sedimentation, coagulation function, blood culture, liver and kidney function, immune function, relevant tests before transfusion of blood products, etc. The prognosis of Kawasaki disease is mostly good. In a few cases, cardiovascular diseases such as coronary artery dilatation and severe aneurysm may persist for several years; aneurysm rupture is life-threatening. Some children may develop cardiac arrhythmias, myocardial damage, or even myocardial infarction.