Patient: first attack on 2008-05-03/vomited twice on the night of 2008-11-16, had fever and diarrhea the next day Coronary arteries are around 4.2/4.3 (I would like to ask how many in normal children)/currently using aspirin I would like to ask if there is a possibility of recurrence of the disease, last night the child had a high fever of 38.4 had a fever-reducing injection which did not subside at the moment, and the current symptoms are Fever 38.4; eye congestion, peeling skin on the hands (in the recent fever before the peeling skin), often diarrhea. Wang Tao, Department of Cardiothoracic Surgery, Qilu Hospital: There is no very specific diagnosis and treatment for Kawasaki disease at present, but the disease can mostly be cured spontaneously after symptomatic treatment in most cases. I wonder where your child was diagnosed? Kawasaki disease has a recurrence rate of 2% to 3%. In children, the normal values of the right and left coronary arteries usually do not exceed 2mm. Let me give you a brief introduction to Kawasaki disease: Kawasaki disease, also known as cutaneous mucocutaneous lymph node syndrome, is an acute febrile illness characterized by skin and mucocutaneous eruptions, enlarged lymph nodes and polyarteritis. The majority of children are between the ages of 2 months and 5 years, but there are also adult patients, with a male-to-female ratio of 1.3 to 1.5:1 and a recurrence rate of 2% to 3%. The etiology of the disease has not been fully elucidated, but genetic predisposition and infection may be the cause of the disease. According to the clinical manifestations and excluding other diseases, the diagnosis can be established if 5 out of the following 6 items are present: (1) persistent fever for more than 5 days. (Fever can last up to 2 weeks to 1 month, and the temperature often reaches 39°C or more-author Wang Tao notes. (Same below) (2) Bilateral conjunctival congestion. (3) Polymorphic erythema. (Mostly occurring on the trunk.) (4) Redness of the lips and mouth Strawberry-like tongue; diffuse congestion of the mucous membranes of the mouth and pharynx. (5) Congestion and sclerotic edema of palms and soles in the acute phase. Peeling of the fingertips begins in the recovery phase (appearing at the skin junction of the nail beds). (6) Acute nonsuppurative cervical lymphoid enlargement. In most cases the disease is self-limiting. In the acute febrile phase, aspirin 30 to 150 mg/kg can be given orally in 3 to 4 divided doses; the dose is adjusted according to the blood concentration of 20 to 30 mg/dl. After the febrile period, the dose can be reduced by 3～10mg/kg once a day; aspirin can slow down coronary artery aneurysm and prevent thrombosis. Frequent electrocardiograms and two-dimensional echocardiographic follow-up should be performed during treatment, and coronary angiography can be done if necessary. The duration of aspirin therapy depends on the clinical course of the disease and is usually appropriate for several months; if a coronary aneurysm develops, treatment should be continued until the aneurysm resolves. The vast majority of children have a good prognosis, with a self-limiting course, and can recover gradually with appropriate treatment.