Kawasaki disease is an acute febrile rash pediatric disease with systemic vasculitis as the main lesion. The main symptoms are fever, rash, bilateral conjunctival congestion, stomatitis, initial hard swelling of the hands and feet and membranous peeling of the finger and toe ends during the recovery period, and swollen lymph nodes in the neck. Symptoms are as follows: (1) Fever: Most of them are persistent, with body temperature up to 39 degrees or more, and ineffective by antimicrobial treatment. (2) Rash: A congested maculopapular skin rash or polymorphic or scarlet fever-like rash appears 2 to 3 days after the onset of fever. (3) Red eyes: Both eyes have congested conjunctiva, usually without secretions (individual children may also have a little eye discharge). (4) Prune tongue: flushed lips with dry chapped or bleeding, and prune-like tongue. (5) Hard edema of the hands and feet: early flushing of the palms and soles of the feet, and large flakes of peeling skin at the junction of the nails at the ends of the fingers and toes about ten days later. (6) More than 70% of children have transient swelling of neck lymph nodes with pressure pain, about the size of a large date or walnut, mostly unilateral, and most of them subside in about 7 to 10 days. (7) Redness and desquamation of the perianal mucosa. The possibility of this disease should be highly noted in children with persistent fever for more than five days, accompanied by rash, stomatitis, and conjunctival congestion.