Triple bilirubin generally refers to total bilirubin, conjugated bilirubin and unconjugated bilirubin, and is mainly used to check whether there is liver disease, bile duct disease and the level of bilirubin. Whether a high bilirubin trio requires treatment or not depends on the degree of bilirubin elevation, the patient’s clinical manifestations, the level of other tests and the cause of the disease. Usually, the total bilirubin value in adult serum is 3.4-17.1μmol/L, the conjugated bilirubin is 0-6.8μmol/L, and the unconjugated bilirubin is 0-6.8μmol/L. If the total bilirubin is above 17.1μmol/L, it is considered as elevated bilirubin. Of course, the metabolism of bilirubin varies from body to body. If the total serum bilirubin is 17.1-34.2 μmol/L by liver function test, there is a slight increase, but no obvious clinical symptoms such as yellowing of the skin and sclera are detected by the naked eye, this situation indicates that the patient may have occult jaundice, which generally does not cause adverse effects on the body and does not require special treatment. If the total bilirubin in the serum is high, but the patient has no obvious clinical symptoms, no other test indicators are abnormal, and there is no clear cause, this situation also does not require special treatment, regular review can be done. If the serum bilirubin is significantly higher than two weeks ago and the skin and sclera are yellowish, abdominal ultrasound should be performed. Combining various test indicators to determine the possibility of viral hepatitis, liver cirrhosis, steatohepatitis and other diseases, we can further confirm the diagnosis and actively carry out relevant treatment according to the specific cause.