What is the cause of hemolysis after blood sampling

Post-phlebotomy hemolysis refers to the situation that blood is dissolved and destroyed in the test tube when blood is drawn for clinical examination, and then it is impossible to do the relevant examination and needs to be drawn again. For example, if the phlebotomist does not handle the blood properly, does not store it properly, or if the blood specimen is violently shaken during transportation, it may cause the red blood cells to lyse and destroy due to the shock, and thus the phenomenon of post-phlebotomy hemolysis may occur. Therefore, post-phlebotomy hemolysis is relatively common and is usually caused by external factors, so there is no need to panic and just redraw the blood. Of course some patients with severe autohemolytic anemia may have their own hemolysis after blood draw, but this is relatively rare clinically.