Ankylosing spondylitis occurs in young men and women, and many patients face many fertility problems, such as: 1. What is the effect of the strong column itself on fertility In fact, regardless of gender, the strong column itself is not a major obstacle to fertility and newborns, and does not increase the complications of the pregnancy process, such as spontaneous abortion, preterm labor, stalled labor, and the occurrence of pre-eclampsia. In women, vaginal delivery is often obstructed by pelvic joint involvement and pain, and cesarean delivery is indicated if the sacroiliac joint is strong. However, due to the slow progression of the lesion, most pregnant women have passed the childbearing stage before the lesion develops to an advanced stage. 2.What is the effect of strong column treatment drugs on fertility The main drugs used for the treatment of strong column are: anti-inflammatory and analgesic non-steroidal anti-inflammatory drugs, such as anti-inflammatory pain, Fotarim, Asimethicin, Meloxicam, Loxone, Cilobal, etc.; basic drugs such as lurasulfapyridine and common slow-acting drugs such as Leflunomide, Paeoniflorin, Thalidomide, etc.; and the latest clinical biologics such as Ixepro, Classic, etc. . These drugs have a definite effect on men mainly is lorazepam, which needs to be stopped 4-6 months before childbirth. Other drugs have little effect and may not be harmful if stopped for 1-2 months before childbirth. Because the pregnancy process is mainly completed by women, the impact of drugs on pregnancy is mainly in women. 3. How to cope with fertility in male patients As long as the spouse gets pregnant, the effect of the disease and its drugs on fertility in men is over. Therefore, patients with salazosulfapyridine stop this drug for 4-6 months, and other drugs stop 1-2 months, it can be, if the disease worsens in the middle of stopping the drug, you can temporarily add non-steroidal anti-inflammatory drugs short-term symptomatic treatment. 4, female fertility and how to cope with the need to be based on different medications before pregnancy, a planned early arrangement to stop the drug. It is best to be under the guidance of a doctor according to the specific situation to deal with separately. The above is for the reference of patients only. When ankylosing patients face fertility problems, it is best to deal with them under the guidance of your doctor.