In menopausal women, due to the gradual decline of ovarian function and the decrease of estrogen level, clinical symptoms may occur. 1. changes in menstruation, changes in color or volume of menstruation, changes in menstrual cycle. 2. hot flashes and excessive sweating. 3. insomnia and sleeplessness, difficulty in sleeping. 4. emotional changes, more sensitive, easily angry, easily agitated. 5. The decrease in estrogen level will lead to a decrease in libido. 6. Due to the decrease in hormone level, the resistance of the vagina will decrease and vaginal inflammation will easily occur. 7. Symptoms of the cardiovascular system will occur, such as palpitations and chest tightness. 8. Due to the decrease in hormone level will lead to osteoporosis, and some people will cause muscle pain throughout the body.