At present, there is no specific antidote drug for succinylcholine poisoning, and the general clinical practice includes general treatment measures and drug treatment measures for antidote. Succinylcholine is commonly used in clinical practice as a skeletal muscle relaxant drug, mainly used for anesthesia before general anesthesia surgery or muscle spasm caused by various diseases. Succinylcholine overdose will cause a series of adverse reactions of the body, at present did not study a specific antidote drug, general therapeutic measures and drug therapeutic measures are generally used to rescue. First of all, the drug should be stopped immediately, if the oral use of drugs and lead to poisoning, need to use sodium carbonate solution or sodium chloride solution in time to induce vomiting, gastric lavage operation, gastric lavage after the end of magnesium sulfate or mannitol diarrhea, in order to reduce the gastrointestinal tract to the residual toxins continue to be absorbed. If the patient has developed severe respiratory paralysis, it is necessary to immediately take artificial respiration or ventilator to assist in the restoration of respiration until the patient’s body metabolizes the toxin to completion. As for drug treatment, diuretics such as sodium chloride solution or furosemide injection are usually used to accelerate the metabolism of the toxin in order to maintain the body’s hydroelectric balance. Succinylcholine overdose or lead to serious adverse body reactions, need to go to the hospital in time to consult a professional doctor to give the correct standardization of the use of drugs, once the adverse body reactions, to take immediate relief measures, so as not to cause further damage.