”Back pain is very uncomfortable, all kinds of posture pain, often wake up in the middle of the night pain, can not sleep, doctor what is wrong with me?” Recently, a handsome guy with back pain was seen. This 32-year-old guy surnamed Ren, who used to work in auto repair, started to have back pain about 10 years ago, and at first he thought it was due to work strain, so he did not pay attention to it. Later, the back pain gradually increased, often waking up in the middle of the night in pain, unable to sleep, so he was in pain. In order to cure the disease, Mr. Ren quit his job a few years ago and went around to seek medical help, moving to more than 10 hospitals, but he did not get a clear diagnosis and effective treatment. Finally, he was diagnosed with ankylosing spondylitis. Ankylosing spondylitis is a chronic inflammatory rheumatic disease involving the spine and peripheral joints, and is caused by genetics, bacterial infections, and immunological abnormalities. The difference between ankylosing spondylitis and lumbar disc herniation is that in patients with ankylosing crestitis, there is mostly low back pain or sacroiliac pain that worsens at rest and decreases after activity, and progresses from the lumbar spine to the thoracic and cervical crest spine as the disease progresses, with pain in the corresponding areas, restricted activity or crest deformity; whereas lumbar disc herniation is localized pain in the lumbar region, mostly accompanied by neuroradiological symptoms that worsen after activity and decrease after rest. Ankylosing spondylitis is an exceptionally painful and disabling disease, the disease was once called the immortal cancer”; prevalent in adolescents, young friends once recurrent low back pain or waking up at night, do not ignore, must promptly go to the hospital to exclude the disease, as long as early detection, early diagnosis, grasp the “golden treatment period “The most important thing is to make sure that you have a good understanding of the disease. The actual fact is that you can find a lot of people who have been in the business for a long time. 1, to reasonably adhere to physical exercise, enhance the strength of the paravertebral muscles and increase lung capacity, swimming is a good adjunct to one of the treatment methods; 2, standing should try to maintain the chest, abdomen and eyes flat in front of the posture; sitting position should also keep the chest upright; should sleep on a hard bed, more supine position, the pillow should be short; 3, feasible acupuncture, hot compresses, massage and other physical therapy; 4, it is recommended that smokers quit smoking, smoking is a functional One of the risk factors for poor prognosis.