Transaminase 60 IU/L is considered high, normal transaminase should be less than 40 IU/L. High transaminase is mostly caused by long-term bad habits. Aminotransferases are the barometer of the liver, which is the main living place of liver cells. When liver cells are damaged, transaminases are released into the blood, resulting in elevated serum transaminases in the body. For patients with transaminases of only 60 IU/L, they can be temporarily observed to find out the cause of the disease and then treat the cause. If it is determined that the elevated transaminases are caused by long-term heavy alcohol consumption, it is important to stop drinking alcohol. If it is caused by chronic hepatitis B and there is an indication for antiviral treatment, antiviral treatment can be considered. An abdominal color Doppler ultrasound is also required when transaminase 60 IU/L is present. If the color Doppler ultrasound of the abdomen is normal, treatment is usually not needed, rest well and recheck in a week. If transaminases are still high, viral hepatitis, steatohepatitis, alcoholic hepatitis and autoimmune hepatitis should be ruled out.