It is an ancestral saying that it is good to go to bed early and wake up early, especially for those who are unfortunately infected with the hepatitis B virus, it is ideal to be able to do without staying up late. According to the current research on hepatitis B, it was found that hepatitis B is not only an infectious and chronic disease, but it was also found that hepatitis B is also an immunocidal disease! In acute severe hepatitis and subacute severe hepatitis patients can be seen in the serious consequences of immunocidal formation of liver necrosis, and in chronic hepatitis stable or hepatitis B virus carriers can also be seen in the immune calm period of “peace and prosperity”. It is true that hepatitis B virus infection does not directly cause disease, but it is possible to form immune killings and cause liver damage when the immune system in the body is not working properly. People, creatures of the earth, are suited to the environmental changes of spring, summer, autumn and winter, day and night on earth. That is to say, sunrise and sunset are the habits of human society for tens of thousands of years, compliance with this law is beneficial to health, and vice versa is not conducive to health. In terms of modern medicine, the general public through a good night’s rest (especially from 10 p.m. to 2 a.m.) can make the immune system to adjust to restore. If you insist on going against the grain, you will pay the price.