Symptoms of esophageal cancer in late stage are as follows: 1. dysphagia: persistent and progressively aggravated dysphagia; 2. food reflux: reflux contains undigested food, mucus, sometimes accompanied by blood, pus and blood; 3. pain in swallowing: pain when swallowing; 4. weight loss, advanced cachexia; 5. other: hoarseness due to tumor compression of the recurrent laryngeal nerve; eruption and phrenic nerve paralysis due to tumor invasion of phrenic nerve; shortness of breath, shortness of breath and dry cough due to tumor compression of esophagus; hemorrhage due to tumor invasion of aorta; esophageal tracheal fistula due to esophageal cancer connected with trachea, resulting in dyspnea, cough and blood cough.