1. Effects of stellate ganglion block on the vegetative nervous system Studies have shown that repeated stellate ganglion block is a resurrection exercise for the vegetative nerves. Blood norepinephrine (NE) is a sensitive indicator of sympathetic nerve activity. Stellate ganglion block has a suppressive effect on excitation of the sympatho-adrenal system. It was found that norepinephrine in serum decreased significantly after planetary ganglion block in patients with pain, cancer, and menopausal syndrome, but remained within normal values. In contrast, in normal subjects, the concentration of norepinephrine in plasma was altered after planetary ganglion blockade, but the difference was not significant. It can be seen that stellate ganglion block only inhibits the increased sympathetic activity and restores the sympathetic-vagal balance. 2, stellate ganglion block on the regulation of the cardiovascular system stellate ganglion block can improve abnormal blood rheological indicators, including reducing the whole blood hyperviscosity and erythrocyte pressure volume, and accelerate blood circulation. Studies have found that vasodilation occurs approximately 5 min after stellate ganglion block, with a peak increase in blood flow of 75% after 15 min and lasting for 70 min, and a 58% increase in blood flow velocity after 15 min and a 7% increase in blood vessel diameter after 60 min. Clinical treatment of cerebral thrombosis patients with He-Ne laser intravascular irradiation therapy using stellate ganglion block can improve the antioxidant index in the body and reduce the content of free radicals, and the laser makes various components in the blood activated to different degrees, while stellate ganglion block dilates blood vessels, improves blood flow at the infarct site, increases the local oxygen content and the content of activated scavenging enzymes, plays a role in inhibiting and blocking the chain reaction of free radicals and reducing the consumption of scavenging enzymes. The stellate ganglion block dilates blood vessels, improves blood flow to the infarct site, increases the local oxygen content and activated enzyme scavenging content, inhibits and blocks the free radical chain reaction and reduces the consumption of scavenging enzymes, and at the same time decomposes and metabolizes a large amount of locally generated free radicals. In addition, it is also used in the treatment of cardiovascular diseases such as Raynaud’s disease, angina pectoris and myocardial infarction. 3.The effect of stellate ganglion block on the endocrine system The nervous system and the endocrine system are closely linked, and the degree of sympathetic tension affects the secretion of various endocrine glands. The pineal gland secretes pinealin (also known as melatonin) periodically throughout the day and night, which affects the body’s sleep and wakefulness. Clinical observations confirm that stellate ganglion block with lidocaine can improve sleep and treat insomnia. Stellate ganglion block significantly reduced the levels of cortisol, aldosterone, angiotensin II, 5-HT, and substance P in the blood of patients with pain. It is easy to see that stellate ganglion block can regulate the abnormal changes of endocrine system. 4.The effect of stellate ganglion block on the immune system Immune function plays a crucial role in the body’s defense, stability and regulation of its own internal environment. In the treatment of chronic non-specific ulcerative colitis with stellate ganglion block, it was found that the immune function of erythrocytes, lymphocytes conversion rate and immunoglobulins such as rosette nodes and immunoglobulins were significantly improved. Stellate ganglion blocks have been reported to be effective in the treatment of allergic rhinitis.