The Yellow Emperor’s Classic of Internal Medicine, the treasure of our medical philosophy, has a clear description of the life cycle of men and women. That is, in general, a woman will have her first menstrual period around the age of 14, and she will become amenorrheic around the age of 49. In other words, at the age of 50, a woman completes the laborious task of childbearing and nurturing, and embarks on a new journey of living for herself. During this transition, some women will have a smooth transition, while others will have “old friends” (menstruation) that will always be “reluctant to give up” or even “unceasing”. “The medical term for this is functional menopausal bleeding. Menopausal women due to the gradual deterioration of ovarian function, can not produce mature follicles and ovulation, thus losing the normal female hormone cyclic changes appear irregular vaginal bleeding. Here need to pay attention to is: female friends can occur in menopause (45 ~ 55 years old) menstrual disorders, irregular bleeding that is menopausal bleeding; but can not be reversed to say that in the menopausal abnormal bleeding, menstrual disorders belong to menopausal bleeding. We need to be alert to organic lesions that cause bleeding, especially endometrial cancer. Not long ago, one of my homegirls who works outside of China called me to consult me about a similar bleeding situation. Her bleeding was heavy and prolonged and had caused her to be severely anemic. She had a diagnostic curettage six months ago at her place of employment, and the pathology was not suggestive of cancer; she was considering disordered menstruation, but the specifics were ominous. She thinks she is chaotic menstruation (menopausal bleeding) hope that I can WeChat to give her a panacea to solve her problem at once. I told her for sure: I don’t have that kind of ability, and suggested that she be hospitalized immediately for a blood transfusion and diagnostic scraping plus symptomatic anti-inflammatory treatment. I was quite lucky that this old country bumpkin belonged to the early stage (endometrioid carcinoma stage 1b) grading 1. Considering her follow-up conditions were limited, plus there was a high-risk factor that the lesion was larger than 3 centimeters. It was suggested that four courses of chemotherapy with TC regimen could be done postoperatively. So, reading this dear you may ask: how far is menopausal bleeding from endometrial cancer? It may be that far …… Women with functional menopausal bleeding present with irregular uterine bleeding, disturbed menstrual cycles, varying menstrual periods, heavier and shorter periods, sometimes drenching menstrual blood for months, and anemia. If abnormal bleeding occurs during menopause, i.e., menstrual cycle disorders, prolonged menstrual drag, heavy menstrual flow, especially ultrasonography suggests that endometrial thickening belongs to the high-risk group. Or postmenopausal bleeding with an endometrium of 4-5mm or more is also a high risk group. Diagnostic scraping and pathologic examination must be required for high-risk groups, because only pathology is the gold standard for all cancer diagnosis. Only when organic lesions are excluded, especially endometrial cancer, can functional menopausal bleeding, also known as menopausal ovulation disorder bleeding, be considered for medication regulation. Therefore, we are reminded not to take for granted that bleeding during menopause is chaotic menstruation, requiring menstrual regulation to stop bleeding, especially not to take medication on their own, that is, without medical treatment, must go to a regular hospital to check, please doctor’s judgment. Women are flowers, a rose, let us open proudly and grow old gracefully! Smoothly and peacefully through each period.