Female menopause syndrome is also called menopausal syndrome refers to a group of symptoms caused by the loss of ovarian function in women around the time of natural menopause or after ovarian destruction due to surgical removal or radiation irradiation, etc. Generally speaking, pre-menopause begins at the age of 45 and lasts for 2 to 4 years before entering menopause, while post-menopause generally lasts for 6 to 8 years, with ovarian hormones decreasing to their lowest level. The changes of menopause actually include two aspects: 1, the decline of ovarian function, the body’s estrogen levels directly on the body’s impact; 2, the body’s aging changes. The two are often intertwined, and the syndrome of neurovascular instability is a prominent manifestation of menopause, mainly related to the decline of sex hormones, but the mechanism of its occurrence is not fully understood. In addition, the occurrence and severity of symptoms of menopausal syndrome are also closely related to individual quality, health status, social environment and psychoneurological factors. Recent studies on neuromediators such as serotonin and dopamine have shown that the cerebral cortex plays a major role in regulating hypothalamic activity through neuromediators. The change of endocrine balance in menopausal women can lead to dysfunction of hypothalamus and vegetative nerve centers, resulting in different degrees of clinical symptoms, especially changes in the function of the vegetative nervous system, and when the level of estrogen decreases, it causes dysfunction of neuromediators through the influence of the enzyme system, in which the effect of norepinephrine is dominant and the function of dopamine is relatively insufficient. The nerve cells are not only regulated by the above-mentioned neuromediators, but also by the local production and action of prostaglandins. In addition, the vascular smooth muscle is also affected by the local production of prostaglandins and shows local tissue congestion and vasodilation. The flushing and sweating of the skin of the face, neck and chest is consistent with the distribution of sympathetic nerves in the neck.