It was the 6th day that Ming Ming’s mother thought he just had a cold, so she went to a small clinic and prescribed some cold medicine, but to her surprise, a red rash appeared on the back of Ming Ming’s hand, and Ming Ming’s mother thought something was wrong, so she took him to the hospital, but after some tests, he was diagnosed with Kawasaki disease. When it comes to Kawasaki disease, many parents don’t know about it, or even have never heard of it. “Kawasaki disease, also known as cutaneous mucosal lymph node syndrome, is a major cause of acquired heart disease in children, so parents need to be especially vigilant. Many parents are not aware of Kawasaki disease, so most of them mistake it for a cold and delay treatment. Fever is the first symptom of Kawasaki disease, and the presence of red dots on the child’s body often leads to misdiagnosis as a cold, measles, or scarlet fever. “Kawasaki disease is not like a cold, which can cause coughing, sneezing, and nasal discharge. In addition, after 3 days of having a cold and fever, the symptoms will be relieved and the body temperature will drop, but children with Kawasaki disease have a persistent high fever, and the body temperature is between 38°C and 39°C. The fever can last for more than 5 days. In general, when a child with Kawasaki disease has a fever for about two days, red rashes of various sizes will appear all over the body, the lips will be dry and cracked, the oral mucosa will be red, and red bumps will grow on the tongue, like the “thorns” of fresh prunes, called prune tongue. If a child has a fever for several days and then has symptoms such as congested conjunctiva, dry red lips, swollen lymph nodes in the neck, skin rash, red and swollen palms or feet, parents should be alert to whether their baby has Kawasaki disease. The current treatment for Kawasaki disease is mainly gammaglobulin infusion and oral aspirin. Most children have a good prognosis for prompt medical attention, but a few may develop coronary artery disease. Therefore, once Kawasaki disease is suspected, the child should be seen promptly and followed up regularly.