Organophosphorus insecticides are cholinesterase inhibitors, which are toxic to both humans and animals. These compounds mainly through the inhibition of the body’s cholinesterase, resulting in the accumulation of acetylcholine in the nerve endings, the effect on the cholinergic receptors of the effector organs, resulting in organ dysfunction. Currently commonly used organophosphorus pesticides are: highly toxic class, methomyl (3911), endosulfan (1059), convective phosphorus (1605), etc.; strong toxicity class: sulforaphane 203 (thiotepe), triflate phosphorus, methyl convective phosphorus and DDV; poisoning class: lexapro, b-liquid phosphorus, trichlorfon, etc.; low toxicity class: malaria-liquid phosphorus, chlorpyrifos, etc. Low toxicity class organophosphorus pesticides general contact rarely cause poisoning, but a large number of people into the human body can still be poisoned. The poisoning class above organophosphorus pesticides can be poisoned through contact, but the degree of poisoning is related to the toxicity of the pesticide, the amount of exposure and contact time. Organophosphorus pesticides enter the human body mainly through the respiratory tract, digestive tract and skin contact, and are absorbed rapidly and completely through the respiratory tract and digestive tract, and typical symptoms of organophosphorus pesticide poisoning can appear within minutes. The degree of poisoning and the symptoms after poisoning depend entirely on the degree of exposure to the pesticide, including the toxicity of the pesticide, the amount of exposure and the duration of exposure. Determining whether a patient is poisoned by organophosphorus pesticides can be done by: 1. Poisoning history: whether the patient was involved in any part of the pesticide production, packaging, preparation and use process. Poisoning may occur if there are improper protective measures or failure to implement safe operating procedures in the above mentioned links. Organophosphorus pesticide poisoning in life is mostly seen in accidental or self-inflicted (attempted suicide), and such patients are not difficult to determine; 2. Odor: Most organophosphorus pesticide poisoners have a garlic-like odor. Patients have garlic-like odor in their mouth, exhaled air, body or vomit; 3. Specific symptoms: Patients with poisoning have muscarinic-like symptoms (narrow pupils, lacrimation, runny nose, salivation, profuse sweating, nausea, vomiting, abdominal pain, diarrhea, cough, sputum, respiratory distress, etc.); nicotine-like symptoms (muscle tremors, muscle spasms, muscle weakness, muscle paralysis, cardiovascular system performance, etc.); central nervous system symptoms (headache, dizziness, irritability, convulsions and even coma). Based on the above analysis, we can basically determine whether the patient was poisoned by organophosphorus pesticides. It can also be judged by special examination when the patient is sent to hospital for resuscitation. For the rescue of organophosphorus pesticide poisoning patients, it is necessary to fight for every second, while rescuing and transferring to hospital: 1. Immediately evacuate the patient from the toxic environment to prevent continued contact with the poison, take off the clothes that stick to the poison, immediately wash the skin thoroughly with slightly warm soapy water (trichlorfon should not use alkaline liquid, because in an alkaline environment, trichlorfon can become more toxic DDV), and pay attention not to scrub the skin with hot water, because it can The skin capillaries dilate and promote the absorption of the poison; 2. Gastric lavage should be performed immediately for those who are poisoned orally. The key to successful rescue of oral organophosphorus pesticide poisoning is timely and effective gastric lavage. Gastric lavage should not be carried out after the arrival of professional rescuers or after being sent to the hospital, but the patient can drink a lot of water or saline and then use chopsticks or spoons to press the root of the patient’s tongue to induce vomiting, and so on repeatedly, remembering not to delay the time of resuscitation by looking for special gastric lavage solution; 3. While carrying out the above treatment, transfer to the hospital and give special antidotes and cholinesterase reenergizer treatment. Cardiopulmonary resuscitation should be performed at the same time for those whose heartbeat and respiration have stopped.