It may be caused by kidney disease such as acute glomerulonephritis.
In patients with kidney disease with abnormal kidney function, a large amount of protein in the blood is excreted in the urine or excess water cannot be excreted, resulting in a decrease in the osmotic pressure in the blood and water in the plasma leaking through the walls of blood vessels to tissues with higher osmotic pressure. oedema is more likely to occur in the eyelid area where the tissue is lax, and oedema may also occur in the hands.
In addition to oedema, patients with kidney disease may also have abnormalities in urine colour, volume and voiding, as well as weakness. Checking for urine protein can be elevated.