Patients with kidney disease have abnormal kidney function, so that a large amount of protein in the blood is excreted in the urine or excess water cannot be excreted from the body, resulting in a decrease in the osmotic pressure in the blood and water in the plasma leaking through the walls of blood vessels to tissues with higher osmotic pressure, the eyelid area is more prone to oedema and swelling of the hands may also occur.
In addition to oedema in the hands and other areas, patients with kidney disease may also have abnormalities in urine colour, volume and voiding, as well as weakness. Checking for urine protein can be elevated.