Swelling of the hand when walking may be caused by strain or trauma. If strenuous activity causes injury to the muscles and ligaments of the hand, swelling of the soft tissue of the hand may occur, and the swelling of the hand may be aggravated by drooping of the hands and poor venous return when walking. Therefore, the affected limbs should be elevated appropriately to avoid prolonged hand droop to aggravate the swelling of the hand. Hand swelling can be applied magnesium sulfate solution for wet compresses, can play a role in eliminating swelling, can also take some oral treatment of Chinese medicine to promote local blood circulation, eliminate swelling. If accompanied by pain, oral anti-inflammatory and analgesic drugs should be taken for treatment, which can relieve the symptoms of pain, and appropriate hot compresses or physiotherapy should be applied to the hand to promote local blood circulation and relieve the symptoms of swelling.