About 20-40% of patients can be asymptomatic for life and are found incidentally during physical examination, surgery, autopsy or other examinations, which is called “resting gallbladder stones” or “asymptomatic gallbladder stones”. Symptomatic gallbladder stones are mainly manifested as follows: gastrointestinal symptoms such as indigestion: after eating, especially after eating fatty food, vague pain and discomfort in the upper abdomen or right upper abdomen, fullness, accompanied by belching, acid reflux, eructation, etc., often mistaken for “stomach disease”. Biliary colic is the typical manifestation of biliary pain, which is often referred to as “biliary pain”, and often occurs after a full meal, after eating fatty foods, or during sleep. The pain is located in the upper abdomen or right upper abdomen and is paroxysmal, radiating to the shoulder blades and back, and is often accompanied by nausea and vomiting.