Liver hardness can directly reflect the health status of the liver. A liver hardness of 12.5 kPa basically indicates cirrhosis or severe liver fibrosis, and the specific survival time depends on the degree of cirrhosis and the effect of treatment. Usually a liver stiffness of 2.5-7.0kPa is normal. A value of 7.0-9.5kPa indicates significant fibrosis in the liver. When the value is in the range of 9.5-12.5kPa, it indicates that the liver shows severe fibrosis. If the value of liver stiffness is 12.5kPa, it basically indicates cirrhosis. Usually cirrhosis has a long course and is divided into compensated and decompensated stages. Patients in the compensated stage of cirrhosis survive for a longer period of time, usually about 10-20 years. Once they progress to the decompensated stage of cirrhosis, the 5-year survival rate is less than 30%. In patients with cirrhosis in the decompensated stage, liver transplantation can significantly improve the prognosis with a 1-year survival rate of up to 90% and a 5-year survival rate of up to 80%. The most common clinical factors leading to cirrhosis are viral hepatitis and alcohol abuse. In daily life, hepatitis vaccination should be given in a timely manner, and a balanced diet, smoking and alcohol cessation, and good living and eating habits should be developed to minimize the risk of cirrhosis.