Patients with mental illness are a special group of people in society. Recently, there have been many incidents of mental illness patients injuring people and doctors, and their aggressiveness and destructive power are unpredictable. Identifying and effectively controlling patients with mental illness is an unshirkable responsibility of all doctors. Cardiology is the hardest hit area for anxious and depressed patients. Patients often present with symptoms such as chest tightness and shortness of breath, but all actual tests are negative and patients show symptoms such as nervousness, anxiety, and worry. As a cardiologist being able to effectively identify and standardize the treatment of such patients is a boon to patients and families. However, clinical underdiagnosis and misdiagnosis often occur, and treatment is not standardized, with most cardiologists only using Dextran. The following major types are common in cardiology: 1) post-stroke depression 2) menopausal syndrome 3) perinatal depression 4) young patients with anxiety and depression In addition, the emergence of new drugs in recent years, which lead to anxiety and depression patients deserve more attention because such patients are more difficult to treat.