According to the World Health Organization, liver damage caused by drugs accounts for more than 5% of hospitalized patients. It is important to know that the liver is an important organ for drug transformation and metabolism, and drugs need to be metabolized by the liver after entering the body by oxidation, reduction, decomposition and combination. The following is a summary of 4 common drug liver injury behavior, we come to see if they have been hit it. 1, five types of drugs should not be taken at the same time Clinical findings, cold and flu medicine, sleeping pills, asthma medicine, painkillers, antibiotics, etc. are most likely to overdose. These drugs have a common feature: many patients take them according to the instructions, but the symptoms are not eliminated in a timely manner as expected, so they will not follow the interval of medical advice to take again, resulting in an overdose. Drugs such as paracetamol (acetaminophen), which are contained in many cold and flu medicines and painkillers under different trade names, are also prone to overlap. Patients are advised not to take a variety of similar drugs at the same time, read the instructions carefully before taking the drug, and if you are not sure, it is best to consult a physician/pharmacist. 2.Multiple drugs used together, the liver is difficult to resist the “double whammy” Many drugs are not too obvious damage to the liver itself, but if used simultaneously with other drugs, the impact on the liver may become greater. When two or even more drugs work together, the liver has a hard time withstanding the “double whammy” and is naturally more likely to be damaged. For example, the combination of allopurinol and mercaptopurine can increase the hepatotoxicity of the drug. Ethanol can also increase the hepatotoxicity of drugs, so alcohol should not be consumed while taking liver-damaging drugs. The U.S. Food and Drug Administration (FDA) has also warned that drinking large amounts of grapefruit juice or fresh grapefruit when taking statin lipid-lowering drugs such as simvastatin, atorvastatin, pravastatin, etc., may contribute to the accumulation of drugs in the body and increase liver damage. 3, do not believe in folk remedies, Chinese medicine also hurts the liver Many people believe that Chinese medicine is mild in nature and has less toxic effects on the body. In fact, traditional Chinese medicine is concerned with the identification of evidence and the combination of drugs to reduce toxicity in order to reduce the impact on the liver. However, some herbs can also be hepatotoxic. For example, compound preparations of Strong Bone and Joint Pills, Dissipative Silver Tablets (Pills), Six Gods Pills, Pueraria Mirifica Soup, Fangfeng Tong Sheng San, Damp Poison Qing, Anti-cough and Asthma Tablets, Niuhuang Detoxification Tablets, Tianma Pills, etc. Moreover, herbal medicines must be strictly identified by herbalists and the amount must be grasped in order to minimize toxicity. Therefore, when taking Chinese medicine or proprietary Chinese medicine, you must find a professional herbalist to consult, not to trust folk remedies and take herbal medicine without permission. 4, children with adult drugs are prone to liver damage In the absence of special dosage forms for children, you may have to give children with adult drugs, at this time must follow medical advice to reduce the amount of use. This is because children’s liver metabolism ability is not as good as adults, adult drugs used on children, the amount is more difficult to grasp, liver damage may occur. For example, paracetamol and erythromycin have been shown to be more likely to cause liver damage in children. It is advisable for parents to choose child-specific dosage forms for their children and not to give them medication based on experience alone, and not to give them adult medication easily. When there is no children’s dosage, it is necessary to seek medical advice and calculate the dosage precisely according to the kilogram weight under the guidance of a doctor in order to prevent liver damage in children.