Syphilis is a sexually transmitted disease caused by syphilis spirochete infection, mostly through sexual intercourse, but under normal circumstances, if the only sexual partner, pay attention to the hygiene of sexual life, generally will not be infected. However, if the above factors are excluded, normal people who get syphilis may also be infected due to mother-to-child transmission, blood transmission, other transmission, etc. 1, sexual transmission: having multiple sexual partners, unsafe sex, or sexual partners who have had unclean sex, etc., is the main cause of infection with syphilis spirochetes; 2, mother-to-child transmission: if the patient is a child, you also need to consider the possibility of mother-to-child transmission. If the mother has syphilis, the fetus is infected with syphilis spirochetes through the placental blood, or through the maternal birth canal during delivery, and then suffer from congenital syphilis, for women with a history of syphilis, need to be examined before pregnancy to reduce the chance of fetal syphilis transmission; 3, blood transmission: input blood with syphilis spirochetes, may be infected with syphilis, while contact with the needles used by syphilis patients, piercing the skin may also There may be a risk of syphilis infection; 4, other transmission: kissing, breastfeeding, or contact with the infected person with syphilis spirochetes of personal items, such as cups, towels, etc., may also lead to infection. The above are the factors that normal people may get syphilis, once the diagnosis of syphilis, should actively cooperate with the doctor for treatment, personal items need to be stored separately to disinfection, to avoid infecting family members.