Depression medication should follow the following principles: 1, depression is a common symptom in mental illness, a variety of mental diseases can appear depressive symptoms, just like fever is a symptom that can appear in a variety of diseases in internal medicine, so a clear diagnosis must be made, the principles of different diagnostic treatment medication is not exactly the same, so the choice of medication should be under the guidance of a professional doctor; 2, the application of antidepressants must reach the therapeutic amount Otherwise, the treatment effect is not good, and may also delay the disease; 3, because depression is a disease prone to relapse, so in recent years the internationally recognized course of antidepressants is generally divided into three phases, acute phase: 3 to 4 months; consolidation phase: 4 to 6 months; maintenance phase: 6 to 9 months. Be sure to adhere to the medication for successful treatment. Long-term treatment is needed for those with long duration, recurrent attacks and residual symptoms; 4. Prohibit drinking alcohol, coffee, smoking, climbing, driving, swimming and working at height during the medication period; avoid abusing other drugs, and if it is necessary to take other drugs, please consult a specialist to avoid adverse reactions between drugs.