The most common cause of large stomach is obesity, mainly through diet control, increase the method of exercise to improve, but also available to take drugs, surgical way to assist in the treatment. In addition, some organic diseases can also have a large stomach manifestations, such as various causes of ascites and Cushing’s syndrome, etc., need to actively treat the original disease: a. Obesity: obesity may cause hypertension, cardiovascular and cerebrovascular disease, diabetes, tumors and other chronic diseases, can lead to abdominal fat accumulation. 1, lifestyle intervention: limit dietary energy, low-fat, low-carbohydrate diet, so that energy intake is lower than the energy consumption. Energy consumption. Exercise therapy combined with diet therapy, do abdominal exercise and whole body aerobic exercise, such as sit-ups, flat support, running, swimming, etc., can make the body in the case of dietary restriction, but still maintain a normal metabolic rate, effectively prevent metabolism weakening, promote energy consumption. In addition, lack of sleep can lead to hormone disorders, decreased body activity, reduced calorie production, increasing the risk of obesity; 2, drug therapy: lifestyle intervention supplemented by drug therapy, weight loss effect is more significant and long-lasting. At present, there are a variety of targeted drugs, inhibit the gastrointestinal tract lipid absorption and other effects, oral probiotics and galactose to reduce abdominal obesity; 3, surgical intervention: abdominal obesity can be serious in the doctor’s advice for surgery, such as abdominal liposuction. Second, ascites: the amount of ascites can be manifested as abdominal bulging, looks like a big stomach. The etiology of ascites is very complicated and needs to be treated for the primary disease, including liver-derived ascites, such as cirrhosis, portal vein system thrombosis, schistosomiasis, etc., as well as oncological, cardiac, renal, biliary, pancreatic ascites, and ascites caused by connective tissue disease and malnutrition, etc., which need to be combined with the history and auxiliary examination to determine, and active treatment of the primary disease. Cushing’s syndrome: typical manifestations of centripetal obesity, full-moon face, polycythemia vera, patients with supraclavicular fossa, back of the neck and abdominal fat accumulation increased, according to the etiology of the corresponding treatment should be done. Such as Cushing’s disease, adrenal adenoma, adrenal adenocarcinoma, mainly through surgical treatment, can be assisted by the application of drugs to block the synthesis of adrenocorticotropic hormone.