Large base weight people lose weight, control diet and exercise is a safer and more effective way, but weight loss should be moderate, step by step. Excessive, too fast weight loss will cause adverse effects on the body, to adopt a scientific and correct way to lose weight. 1, diet: to eat reasonably, planned and gradually reduce the amount of food and drink, not excessive dieting, so as not to cause hypoglycemia. Promote less salt, less oil, less sugar diet, such as reducing the intake of rice, bread and other staple foods, eat more fiber-rich coarse grains, fruits and vegetables. Balanced diet with a balanced diet every day in accordance with the customized diet plan, balanced arrangement of diet; 2, exercise: large base weight loss is easy to injure, the amount and intensity of exercise should be moderate and reasonable, to avoid some more than the body’s load capacity of the movement, such as jumping rope, climbing, etc., so as not to cause damage to the joints. It is recommended to carry out swimming, aerobic running and other sports, which are not obvious for the joint damage, and you can do some stretching preparation before exercise to avoid injury. If obesity has affected the patient’s life and health, only through surgical treatment can solve the problem, we should consider early weight loss surgery. If the patient is excessively obese due to disease, he or she should also actively treat the primary disease that caused the obesity. Large base weight people are prone to diseases of the cardiovascular and cerebrovascular system, but also affect the quality of life, to carry out correct and effective weight loss is necessary, moderate weight loss can reduce the risk of obesity and its complications, but also improve the health of patients.