Farting is also known as defecation, after taking orlistat, the occurrence of frequent defecation, stool with oil, etc., mainly for the common gastrointestinal reaction after taking the drug. Orlistat is a gastrointestinal lipase inhibitor, can inhibit the absorption of triglycerides, and make the body unabsorbed triacylglycerol excreted, and then appear in the discharge of fat and so on. It can also be used to achieve weight control and reduce risk factors associated with obesity by reducing the body’s intake of calories. Most patients may experience increased flatulence, urgency in bowel movements, and symptoms such as steatorrhea, oily stools, or increased frequency of bowel movements, fecal incontinence, and severe abdominal pain, watery stools, and rectal pain. Usually, depending on the degree of tolerance to the drug and the severity of the adverse effects, you can choose to continue using the drug or stop using the drug under the advice of a medical professional. If the patient can tolerate Orlistat and the adverse effects are mild, the drug can be continued, but it is necessary to avoid causing electrolyte and water disorders. If patients cannot tolerate orlistat and experience serious adverse reactions, such as severe abdominal pain, jaundice, and dark urine, the drug should be discontinued at the patient’s discretion. Patients should also undergo regular liver function tests while taking the drug to prevent liver impairment.