1. Regular follow-up and evaluation Kawasaki disease complicated by coronary artery dilatation, coronary aneurysms, especially those ≥6 mm in diameter, or combined with coronary artery stenosis, thrombosis or coronary artery occlusion, is prone to acute coronary events, including angina pectoris, acute myocardial infarction, and even sudden death. Long-term chronic myocardial ischemia can also cause myocardial fibrosis, heart enlargement, and cardiac insufficiency. Therefore, in addition to the long-term use of small doses of aspirin and other drugs to prevent blood clots, regular follow-up should be performed. In case of severe coronary artery lesions, it is recommended to have a comprehensive examination every 3-6 months to assess the presence of myocardial ischemia and the need for anti-myocardial ischemia, anti-heart failure, coronary artery revascularization treatment, etc. 2.What are the circumstances that require additional warfarin, how to calculate and monitor the dose of warfarin, and what are the precautions? Coronary artery aneurysms ≥6mm in diameter, especially giant coronary artery aneurysms ≥8mm in diameter, are prone to combined coronary artery stenosis, thrombosis, calcification, and even occlusion. Patients in this part, as well as those with a history of acute myocardial infarction and rapid coronary artery dilation with thrombosis, may consider adding heparin and warfarin anticoagulation therapy on top of low-dose aspirin. The pediatric dose of warfarin is 0.05-0.12 mg per kg body weight per day, and the therapeutic goal is to maintain a blood INR between 2.0 and 2.5. Warfarin doses vary widely among individuals, with a greater range of dose variation in children, and are easily influenced by other medications and the type and amount of food ingested. For example, drugs such as aspirin, chloral hydrate and clopidogrel can enhance the anticoagulant effect of warfarin. Some green leafy vegetables, which are rich in vitamin K, can reduce the effect of warfarin. Excessive doses of warfarin can lead to bleeding tendencies, which can cause life-threatening gastrointestinal hemorrhage and intracranial bleeding in severe cases. For this reason, it is important for doctors to educate parents or guardians of children taking warfarin so that they can closely monitor the effects of warfarin treatment together with their parents or guardians. The child should also be advised to avoid traumatic situations such as contact with knives, scissors, and other sharp instruments, and to participate in strenuous and impactful activities. 3.What do I need to pay attention to in my life if I have a child with coronary complications? For children with severe coronary artery damage, doctors need to provide life guidance to the children and their parents to prevent early onset of coronary artery sclerosis based on coronary artery lesions in Kawasaki disease, which may aggravate the disease. It is recommended to start cultivating a healthy lifestyle from a young age, including healthy diet and lifestyle habits, such as reducing the intake of high-fat, high-salt and high-sugar foods, moderate activity according to coronary artery lesions, controlling weight, preventing obesity, actively preventing and controlling hypertension and abnormal glucolipid metabolism, etc. For children with serious coronary artery lesions, attention should also be paid to controlling the amount and intensity of activities and limiting strenuous activities. 4.In addition to antithrombotic therapy, what other medications are needed? For children with manifestations of myocardial ischemia and a history of myocardial infarction, calcium channel blockers, beta-blockers, and nitrates should be given to prevent the occurrence of coronary events. In children with combined cardiac enlargement and cardiac insufficiency, additional anti-heart failure drugs are required for treatment, such as renin-angiotensin inhibitors (ACEI), renin-angiotensin receptor antagonists (ARBs), and beta-blockers. 5.When do interventions and bypass surgery need to be performed? In addition to the long-term use of small doses of aspirin and other drugs to prevent thrombosis, a comprehensive examination should be performed every 3 to 6 months to assess the presence of myocardial ischemia and the need for coronary revascularization therapy, especially for coronary aneurysms ≥6 mm in diameter or combined coronary stenosis. If there are symptoms of myocardial ischemia (such as angina), changes in myocardial ischemia on ECG or echocardiography, or evidence of myocardial ischemia on cardiac stress tests (such as stress myocardial perfusion imaging, stress ECG or stress echocardiography), further coronary angiography is required to understand the coronary artery lesions and to assess the necessity and feasibility of coronary revascularization therapy. The purpose of coronary revascularization is to restore blood flow to myocardium at risk of ischemia in order to prevent myocardial ischemic infarction, myocardial fibrosis, myocardial remodeling, cardiac insufficiency and arrhythmias, and to improve prognosis. Methods include interventional therapy or coronary artery bypass grafting (commonly known as bypass surgery). Briefly, the following are the indications for coronary artery revascularization: (1) Symptoms of myocardial ischemia, including subjective symptoms and corresponding examination findings. (2) Evidence of myocardial ischemia on stress tests (including stress myocardial perfusion imaging, electrocardiogram or echocardiogram, etc.) despite the absence of myocardial ischemia. (3) Coronary angiography shows 75% or more stenosis of the coronary arteries; 50% or more stenosis of the left main stem, with risk of sudden death. Of course, whether this can be implemented or not, the age of the child and the specific feasibility of various treatment methods should be fully considered, see the relevant article for details.