Method 1: HBIG 100u (intramuscular in the buttocks) within 12 hours of birth, along with the first dose of hepatitis B recombinant yeast vaccine 10 micrograms (intramuscular injection in the right upper arm triangle), and the second and third doses at 1 month of age and 6 months of age. This method is suitable for babies born to mothers with minor triplets, HBVDNA negative or low viral load. Method 2: Newborns whose mothers are double positive for HBsAg and HBeAg and have high HBVDNA should be given 100iu of hepatitis B immunoglobulin within 6 hours after birth and a booster dose of 100iu after 1 month with the consent of the guardian under the principle of informed consent and voluntariness. one injection of hepatitis B recombinant yeast vaccine (10ug each time, total of three times). These combined active+passive immunization measures are more than 95% effective in interrupting mother-to-child transmission of hepatitis B. Therefore, we say that hepatitis B mothers can also have healthy babies. Hepatitis B mothers should have their liver function rechecked 1 month and 3 months after delivery to detect any postpartum hepatitis activity in time. The baby should be checked once at 9 months of age for quantitative two-to-one half or HBsAg and anti-HBs.