There are about 1,000 kinds of drugs, including herbal medicines and health products, that cause drug-induced liver damage, and most of them are reversible when used in a standardized way. Han Qingrong, Department of Infectious Diseases, Zhangqiu Municipal People’s Hospital On the one hand, part of the drug liver damage is predictable. Drugs themselves have a certain degree of hepatotoxicity, and generally drugs in the instruction manual have indicated that “there is a certain effect on the liver”. The effect of these drugs on the liver is generally related to the dose and time of taking, once the dosage is too large or the time of using the drug is too long, it can cause accumulation of toxicity to the liver. On the other hand, more pharmacologic liver damage is unforeseeable. If the patient belongs to the allergic body and cannot tolerate the drug, even if the dosage is within the commonly used range, it can cause liver damage. Common drugs that have an effect on liver function include: 1. antibiotic drugs, such as amoxicillin, Pioneer IV, chloramphenicol, rifampicin, sulfonamides, etc.; 2. antipyretic and analgesic anti-inflammatory drugs, such as aspirin, paracetamol, fenpropidone, anti-inflammatory pain, sialadenosine and so on. 3. Central nervous system drugs; 4. Hormonal drugs, eugenol, tabazol, hyperthyroidism, danazol. 5. Anti-tumor drugs; 6. Other drugs, such as methyldopa, cardioplegia, cimetidine, cholestyramine and so on.