Symptoms of advanced esophageal cancer include: 1. difficulty in swallowing, which is a typical symptom of advanced esophageal cancer and will gradually worsen, starting from not being able to swallow dry food, then not being able to swallow semi-liquid food, and finally not even being able to swallow water. 2. hoarseness, which will affect the laryngeal nerve in the advanced stage of esophageal cancer and will lead to hoarseness. 3. If the cancer cells spread to other parts of the body, it will lead to long time chest pain or back pain. 4. jaundice and ascites, if the cancer cells metastasize to liver, intestines and stomach, jaundice and ascites will appear. 5. respiratory infection, if the cancer cells spread to trachea and esophagus, such as causing tracheoesophageal fistula, the function of these organs will be affected, and the food eaten will reflux to the respiratory tract and cause food will reflux to the respiratory tract to trigger infection.