Liver fibrosis is the body’s repair response to chronic injury and is an active stromal proliferation pathological process. Recent studies have shown that liver fibrosis is reversible, and some drugs can promote the reversal of liver fibrosis. For example, antiviral therapy for hepatitis B can help improve liver histology, including the reversal of liver fibrosis; anti-inflammatory therapy is an important measure against liver fibrosis; at the same time, etiology and anti-inflammatory therapy are not equal to or a substitute for anti-fibrotic therapy in the narrow sense, which targets extracellular matrix and hepatic stellate cell activation, and inhibits hepatic extracellular matrix production and deposition and promotes its degradation It is an important countermeasure of anti-liver fibrosis treatment. The comprehensive pharmacological effects of multi-channel, multi-level and multi-target are the characteristics of anti-liver fibrosis with multi-component Chinese medicine compound, which has obvious advantages and broad application prospects.