The goal of ankylosing spondylitis treatment care is to try to delay the course of the disease and reduce the occurrence of deformities. Psychological care: This disease is an insidious chronic progressive arthropathy. Educate the patient about the disease, understand the prevention and treatment methods, carry out treatment and exercise as required, and master the methods of self-care. This is especially important to reduce joint dysfunction and delay the course of the disease until the patient can participate in normal work and study. Basic principles of activity: early and appropriate activities can reduce the degree of spinal and joint deformity. Flexion and extension of the spine and hip should be performed twice daily, with each activity limited to the amount that does not cause an increase in joint symptoms the next day. The paravertebral muscles should be massaged and loosened before the activity, which can reduce pain and prevent muscle damage. Meanwhile, physiotherapy methods such as hydrotherapy and ultrashort wave can play a role in relieving muscle spasm, improving blood circulation and anti-inflammatory and pain relief. Delay the care of thought sense deformity: maintain upright posture and normal height. Sleep on low pillows to reduce cervical forward bending. Sleep on a hard bed. Pay attention to reducing the weight-bearing of the spine and avoiding long-term bending activities. Patients who are overly obese should reduce their weight so as to reduce the burden on the joints. Prevent infection: Due to the involvement of the thorax, lung infection is prone to occur, so chest expansion and deep breathing should be performed daily. For patients who are unable to take care of themselves, they should be turned and patted on the back and encouraged to cough. At the same time, pay attention to supplemental nutrition to strengthen the body’s resistance. In the case of uveitis, flush the eye regularly to keep the conjunctival sac clean and the eye should not be covered to avoid infection. Medication care: During the application of salazosulfapyridine, blood picture should be checked regularly, and protective isolation measures should be taken for those with reduced granulocytes. Also check the liver and kidney function regularly to enhance the protection of liver and kidney function.