Paraquat (PQ) (trade name: Paraquat, Gramoxone, etc.): It is a highly effective non-selective contact herbicide with rapid onset of action after spraying and rapid inactivation after entering the soil. Paraquat is very toxic to humans and animals, and acute poisoning caused by misuse or self-inflicted has occurred repeatedly, with an increasing trend in recent years, especially in developing countries, and has become a common cause of pesticide poisoning deaths. Although there are no official statistics on paraquat poisoning in China, according to many literature reports, paraquat poisoning is now one of the most common pesticide poisonings and has become the second most common type of pesticide poisoning after organophosphorus pesticide poisoning and the first in absolute number of deaths in the emergency departments of some hospitals. Due to the toxicity of paraquat to humans and animals and the lack of special treatment methods after poisoning, the widespread use of paraquat has attracted the attention of many international organizations and environmental protection departments, especially the opposition of medical scholars in developing countries. Some EU countries have banned the use of paraquat within their borders and some developing countries have also joined the ranks of rejecting its use. Paraquat toxicity affects many organs of the body: in severe cases, it can lead to multiple organ insufficiency syndrome (MODS), of which the lung is the main target organ and can lead to “paraquat lung”, which is characterized by acute lung injury (Au) or acute respiratory distress syndrome (ARDS) in the early stage and intra-alveolar and interstitial fibrosis in the later stage. Paraquat poisoning is the main cause of death in patients, with a death rate of 50% to 70%. There is no effective antidote for paraquat poisoning, many treatment methods are still being explored, and there is no evidence of evidence-based medicine, and there is no unified treatment plan or guideline for acute paraquat poisoning in China. In order to standardize and guide clinicians at all levels in the practice of acute paraquat poisoning, many experts from the Emergency Physicians Branch of the Chinese Medical Association reached a consensus on the diagnosis and treatment standards for acute paraquat poisoning.