There are certain targeted drugs for esophageal cancer, similar to those for stomach, such as Apatinib. At present, the treatment is precise treatment, after the tumor is removed or blood test is done for genetic testing, some target testing is done according to the target drugs on the market, and according to the genetic test results, targeted drugs are further used, which is a more targeted treatment and a relatively new concept. Therefore, if there are targeted drugs for esophageal cancer, the effect may be better if targeted drugs are used according to the positive results after genetic testing. In the treatment of esophageal cancer, when targeted drugs are used, it is usually the advanced stage of esophageal cancer, and it is recommended to use chemotherapy, radiotherapy, targeted therapy and immunotherapy as the main comprehensive treatment.