The symptoms of hiccups in esophageal cancer patients may be caused by the following reasons: First, the symptoms of hiccups in esophageal cancer patients may be due to the invasion of diaphragm by malignant tumor tissues, which causes diaphragm spasm, inflammation or compression, resulting in stubborn spasm of their diaphragm, and patients will have occasional or prolonged hiccups. Secondly, hiccups of esophageal cancer patients may also be caused by malignant tumor causing their poor digestive function, or excessive gas production in the stomach and acid-base imbalance, causing hiccups and discomfort. Thirdly, due to malignant tumor, patients with esophageal cancer may also experience hiccups due to their excessive mental stress and tension. Therefore, it is recommended that patients must seek medical treatment in time and can relieve their symptoms through medication or acupuncture and Chinese medicine treatment, etc.