Acidosis is divided into respiratory acidosis and metabolic acidosis, which are caused by different etiologies and have different clinical manifestations due to different primary diseases. From their clinical manifestations, patients with mild acidosis show weakness, shortness of breath, fatigue, nausea, dizziness, which can affect appetite, poor appetite, drowsiness, and slightly deeper and faster breathing. More obvious acidosis can appear with cherry red lips, deep breathing, rotten apple smell in the breath, flushed face, fast heart rate, arrhythmia, decreased blood pressure, reduced muscle tone, and decreased and absent tendon reflexes. In severe cases, coma, shock, and even cardiac and respiratory arrest may occur.