Whenever there is a wedding celebration, people inevitably raise a glass to drink together. Occasionally drink some low concentration of alcohol in moderation, there is no harm to health. However, now that living conditions are better, some people are like a holiday drink every day, a drunkenness, but do not know that this action is very harmful to health. Excessive alcohol abuse and death from acute alcohol poisoning is heard from time to time. Long-term heavy drinking can lead to liver damage. Why does excessive alcohol consumption lead to liver damage? This is because alcohol (ethanol) and its transformer acetaldehyde in the body are toxic to liver cells, causing lipid peroxidation, producing toxic oxygen, and destroying the detoxification function of oxygen radicals, leading to hypoxia in liver cells, causing changes in the structure and function of liver cells, and causing inflammation in the liver; ethanol and acetaldehyde also disrupt fat metabolism in the liver, causing triglycerides to accumulate in the liver and forming a fatty liver; the liver, under the repeated stimulation of inflammation Under the repeated stimulation of inflammation and acetaldehyde, fibrous tissue proliferates and eventually develops into cirrhosis due to liver fibrosis. What liver diseases can be caused by alcohol abuse? Alcoholic fatty liver: insidious onset, generally asymptomatic; in severe cases, hepatomegaly and mildly elevated transaminase activity; in severe cases, symptoms similar to hepatitis such as weakness and anorexia may occur. 2. Alcoholic hepatitis: clinical manifestations are similar to viral hepatitis or toxic liver injury, varying in severity, from asymptomatic in mild cases to liver failure in severe cases. In general, patients often have obvious weight loss, nausea and vomiting, loss of appetite, abdominal pain and diarrhea, generalized lethargy, etc.; 80% of patients have liver enlargement and tenderness, and may also have fever, jaundice, splenomegaly, dull face, or even ascites, swelling, and neurological symptoms (liver failure). 3, alcoholic cirrhosis: progressed from alcoholic fatty liver and alcoholic hepatitis, clinical manifestations are similar to post-hepatitis cirrhosis. similar to post-hepatitis cirrhosis. In addition, alcohol plays a facilitating role in the formation of liver cancer. Are people who do not drink with a red face more likely to get alcoholic liver disease than those with a red face? Yes. About half of Asians lack the enzyme ethanol dehydrogenase, and the ethanol they consume cannot be converted into acetaldehyde, so the concentration of ethanol in the blood is high, causing the blood vessels to dilate and cause redness. People who blush when they drink are more likely to get drunk, drink less, and have a lower concentration of acetaldehyde in their bodies, so their liver damage is less severe than those who binge drink because they do not blush. Should I stop drinking if I have liver disease? The answer is yes. In the case of liver disease caused by alcohol, of course, the first step is to remove the cause of the disease (quit drinking), and then the treatment will be effective. For those who already have other liver diseases, the disease is already difficult to treat, so if you drink alcohol again, you are bound to increase the degree of liver damage, just like pouring oil on a fire. In short, people with a family history of liver disease, even though they do not have liver disease, but the hidden memory, do not use alcohol to trigger liver disease. For the sake of your health and the well-being of your family, please do not drink alcohol or drink as little as possible.