Ankylosing spondylitis is a disease in which inflammation of the sacroiliac joints and spinal attachment points is the main symptom, and if not treated in time may result in ankylosing deformities of the spinal joints. In the current medical level, ankylosing spondylitis can be treated, although not cured, but with systematic treatment can completely avoid ankylosing deformity of the joints, patients can live and work as normal people. Ankylosing spondylitis occurs in young and middle-aged men and is characterized by pain, stiffness and functional limitations of the spinal joints, as well as multiple lesions in the eyes, lungs and peripheral joints, which can seriously affect the patient’s daily life. With the improvement of medical treatment, there are more treatments for ankylosing spondylitis, such as medication, functional exercise, and physical therapy. Drug therapy is the basis of ankylosing spondylitis, commonly used anti-inflammatory painkillers, immunosuppressants, biological agents, etc., can reduce joint pain to delay the development of the disease. Functional exercise is important in the treatment of ankylosing spondylitis, and patients should usually maintain the normal position of the spinal joints, such as maintaining thoracic mobility and maintaining normal respiratory function. Physical therapy can be done with medicated baths, steam fumigation, ultrasound, laser, etc. Therefore, ankylosing spondylitis is not only treatable, or can be effectively controlled, patients must establish confidence in the treatment.