Evidence of nutritional metabolic deficiency disease lesions such as a history of malnutrition with niacin vitamin B1 and folic acid deficiency, signs and symptoms of nutritional metabolic deficiency leading to corresponding functional abnormalities, these can be used as diagnostic conditions for nutritional metabolic disease associated mental disorders. Nutritional metabolic deficiency can be diagnosed by the following tests: 1. Newborn disease screening Newborn disease screening is an easy, rapid and inexpensive blood spot test, through which children can be detected early whether they are suffering from congenital genetic diseases and treated in time for their healthy growth. Some congenital metabolic disorders, although their incidence is very low, can seriously affect intellectual development and can lead to lifelong disabilities. They cannot be diagnosed before birth and have no symptoms early after birth, but once the abnormalities appear, the nervous system has been irreversibly damaged and the opportunity for treatment is lost. If you can check early after birth, early detection, early treatment, the child can be protected from damage to avoid mental retardation. 2.Cranial CT examination Cranial CT examination is a method of examining the cranial brain through CT. It can clearly show the anatomical relationship between different cross-sections of the skull and the specific brain tissue structure. Thus, it greatly improves the detection rate of lesions and the accuracy of diagnosis. In general, CT has better visualization of human hard tissues than soft tissues. CT cranial examination is important for the diagnosis of most diseases in the skull, skull and scalp (including trauma, tumor, inflammation, vascular lesions, poisoning, degenerative and metabolic diseases, etc.). 3.EEG EEG is a graph obtained by amplifying and recording the spontaneous biopotentials of the brain from the scalp through an instrument. EEG has diagnostic significance for brain diseases. Abnormal EEG can be divided into mild, moderate and severe abnormalities. Brain Doppler ultrasound (TCD) is a method to examine the brain through brain Doppler ultrasound. Transcranial color Doppler imaging: via temporal window, occipital window and orbital window exploration, the cerebral arteries can be explored and determined according to the flow velocity, frequency width, abnormal flow direction or audio abnormality of intracranial vessels, etc. It is applied to the diagnosis and etiological classification of cerebrovascular diseases. 5.Body organ function and nutrition Body organ function and nutrition are closely related to food intake, digestion, absorption and metabolism, etc. Good or bad can be used as one of the criteria for identification and degree of disease, as well as one of the criteria for diagnosis of body organ function.