With the increasing standard of living of people, the incidence of gallbladder stones in our country is increasing year by year. If gallbladder stones cause blockage of the gallbladder duct, it can lead to a significant increase in the size of the gallbladder and an increase in the pressure in the gallbladder duct, and the patient may have clinical symptoms of pain in the right upper abdomen, nausea and vomiting. What should be done clinically for patients with gallbladder stones accompanied by nausea and vomiting? Once patients with gallbladder stones have nausea and vomiting, different treatment methods should be adopted according to the specific causes and clinical symptoms of vomiting. 1.If the stones in the gallbladder cause blockage of the gallbladder duct and cause reflex nausea and vomiting. At this time, patients can be given intravenous infusion of antiemetic, scopolamine, omeprazole and other drugs to release the bile duct spasm, antiemetic, protection of gastric mucosa and other supportive treatment. Most patients can quickly relieve the symptoms of nausea and vomiting, if the patient’s vomiting symptoms are more intense, you can consider performing gastrointestinal decompression, suction out the gas and liquid in the stomach to reduce the pressure of the stomach, which can better improve the clinical symptoms of patients. If the patient with gallbladder stones has chronic gastritis or gastric ulcer, and vomiting occurs due to stomach spasm caused by inflammation of the gallbladder, it is recommended that the patient be infused with cefamandole or cefmetazole and other anti-inflammatory drugs to strengthen anti-infective treatment to control the inflammation of the patient’s gallbladder in a timely manner, and at the same time, the patient should be given oral Daxi tablets and colloidal bismuth to protect the gastric mucosa. If necessary, minimally invasive biliary laparoscopic surgery can be performed to remove the gallbladder, which can completely remove the infection in the abdominal cavity of the patient and improve the symptoms of vomiting, which can often achieve better clinical results.