Pharmacological treatment of ankylosing spondylitis includes non-steroidal drugs, antibacterial agents, immunosuppression and other non-pharmacological treatments include physical therapy, acupuncture and massage, surgical treatment, psychotherapy, radiofrequency thermal coagulation analgesia, functional rehabilitation therapy, etc. Small acupuncture treatment when local treatment is featured. The methods used are: 1, small needle knife relaxation of soft tissues in the back of the neck: the patient takes a sitting or prone position, aseptic operation, first of all, 2% lidocaine and trimethoprim for analgesic solution for relaxation site injection, in the atlantoaxial spinous process to the seventh cervical spine spinous process on the diagnosis of sensitive pressure pain points, mechanization points, popping points and calcification points, small needle knife incision line and the top line of the cervical spine spinous process parallel, the needle body and the neck plane at an angle of 90 degrees into the needle vertically The needle was inserted vertically at an angle of 90 degrees with the cervical plane, reaching the cervical spinous process bone surface, making left and right transverse stripping and loosening, and after retreating the small needle knife to the mechanized and calcified points of the collar ligament, making longitudinal incision and loosening. Palpate the distribution of superficial muscles and deeper semispinal muscles such as the margins of both sides of the collar ligament, trapezius, cephalicus, scapularis, and rhomboid muscles to determine the contracture of muscle fiber tissues, mechanized points, and the range of swollen pressure pain, and use the small needle knife to make incision and release of these injury points, and make small transverse cuts to release the larger sclerotic points. In the cervical spinous process line, the extra-occipital convexity and concavity is the entry point, the needle body is perpendicular to the skin plane of the entry site, the knife line is perpendicular to the longitudinal axis of the cervical vertebrae, and the left and right transverse cuts are made to loosen the atlanto-occipital fascia for several knives. 2, soft tissue around the thoracolumbar spine small needle knife loosening: select the thoracic and lumbar spinal space with pressure pain or the posterior convexity deformity of the spine, routine aseptic operation, first inject analgesic solution in the loosening site, then use a small needle knife No. 4 to loosen the supraspinous ligament, interspinous ligament and other tissues. The needle was inserted from the left and right side points of the interspinous with a No. 3 small needle knife, and the direction of the needle was adjusted to release the soft tissues between the transverse processes, the tissues around the upper and lower articular processes, and the sacrospinous muscle, respectively. 3, small needle knife loosening of soft tissues around the lumbar transverse process: the patient is in prone position, and pressure pain points (i.e. adhesion points) are identified at the transverse processes of the lumbar vertebrae (with the tip of the third lumbar transverse process) as the needle entry points (in the same cross-section as the corresponding interspinous space), with routine aseptic operation, firstly inject analgesic solution around the transverse processes, and try to enter the needle after the small needle knife is inserted rapidly and vertically about 1cm with the small needle knife incision line parallel to the longitudinal axis of the human body When the tip of the needle touches the bone surface, first perform transverse stripping slightly medial to the tip of the transverse process, then move the knife to the tip of the transverse process for longitudinal cutting and stripping, when there is a loose feeling between the tip of the transverse process and the surrounding adherent muscles and fascia, the needle can be discharged, and then cover the needle hole with a band-aid. 4, soft tissue around the hip joint small needle knife relaxation: the patient is supine or lateral, from the front side into the needle, choose the inguinal ligament under the considerable hip joint projection, should avoid the femoral nerve, artery and vein. Generally, the anterior side is selected for 3 to 4 points of small needle knife longitudinal decompression of the joint capsule. In the lateral approach, the hip joint projection and the tip of the greater trochanter with its anterior and posterior sides are also selected, and 8 to 9 points of small needle knife are selected each time to release the local soft tissue. Patients with ankylosing spondylitis in the middle and early stages are treated with small acupuncture, the symptoms improve more obviously, but the patient needs to adhere to functional exercises to consolidate the effect, while for patients with advanced ankylosing spondylitis small acupuncture treatment, although the symptoms are temporarily reduced, but because the patient can not perform functional exercises, so the effect is not ideal.