(1) The experience of alcohol dependence Most of the patients have a happy mood in the early stage, enjoy socializing after drinking, promote social interaction, relieve tension or fatigue, resulting in “habitual drinking”. (2) Mental dependence The general craving for alcohol in the early stage, to the emergence of obvious physical dependence, the development of more serious, the patient fear of withdrawal symptoms, there is a strong and compulsory thirst for alcohol, resulting in strong alcohol-seeking behavior. (3) Somatic dependence Refers to repeated alcohol consumption that causes certain physiological and biochemical changes to occur in the central nervous system, resulting in the need for alcohol to persist in the body to avoid withdrawal syndrome symptoms. The symptoms of alcohol dependence vary in severity and depend on many factors, such as the amount of alcohol consumed, the type of alcohol, the time and manner of drinking, race and individual quality. If the amount, time and occasion of alcohol consumption are not taken into account, and the amount of alcohol consumption is pursued arbitrarily, the patient is already in alcohol dependence. The monotony of drinking behavior, drinking in the same way to maintain high levels of alcohol in the blood. Patients try to control alcohol consumption in consideration of all the harm it causes, but they cannot control it. The patient develops to the point where drinking becomes the center of all activities and is in a state of continuous drinking. (4) Withdrawal syndrome is divided into early and late withdrawal symptoms. Early withdrawal symptoms include anxiety, unpleasantness, depression, nausea, vomiting, loss of appetite, chills, sweating, palpitations, frequent pulse, hypertension and other vegetative symptoms. There may also be sleep disorders such as nightmares, light sleep, and difficulty falling asleep. Tremor is a typical symptom of withdrawal in alcohol-dependent patients, often occurring 7 to 8 hours after weaning from alcohol. Chronic patients often have morning tremor of the middle finger and eyelids, and in severe cases, they cannot chew and stand unsteadily, which is also one of the early withdrawal symptoms. Delirium tremens, which often occurs 72-96 hours after alcohol withdrawal, is one of the late withdrawal symptoms. (5) Tolerance Refers to the fact that drinking the original amount of alcohol does not achieve the expected pharmacological effect, and the dosage must be increased to achieve it. Tolerance to alcohol increases slowly and to a moderate degree. Generally, it reaches an average high level in young adulthood, and then decreases with the increase of intoxication and age. Continuous drinking episodes do not occur in old age. (6) Some behavioral characteristics of long-term alcohol-dependent people drink a lot of alcohol in a short period of time regardless of time and place, and the amount of alcohol can continue to exceed 150 ml of pure alcohol per day, and they claim to quit drinking many times without being able to interrupt. There are also long-term dependents who drink alcohol→drunkenness→sleep→sober→drinking→drunkenness→sleeping, and repeatedly such drinking periods. (7) Physical complications The main manifestations are neurological, digestive and cardiovascular system damage and sexual dysfunction. Neurological manifestations include tremor, peripheral neuritis, tendon reflex hyperactivity, and positive pyramidal fasciculus pathology. Gastrointestinal system damage includes chronic gastritis, gastric or duodenal ulcer, hepatitis, liver cirrhosis, gastric bleeding, etc. Cardiovascular system damage, myocarditis, coronary artery disease, hypertension are common. Sexual dysfunctions are mainly hypersexuality and impotence.