Surgical treatment of infantile spasms

  The child began to have seizures at 8 months after birth, presenting with dozens or even hundreds of seizures per day. Four antiepileptic drugs and hormone therapy were tried at the local hospital and our hospital, but none of them were effective. The disease progressed rapidly over a period of 4 months, with the child having increasingly severe seizures and exhibiting regressions in development such as language and motor responses. The child was diagnosed with infantile spastic epilepsy syndrome. This is a severe form of epileptic encephalopathy in which seizures are often difficult to control, seizures often severely affect the child’s Chilean development, and the prognosis is often poor.  The seizures were determined to be caused by a microscopic lesion in the deep left temporal lobe of the child. This subtle finding further strengthened the Epilepsy Center team’s decision to treat the child’s epilepsy surgically. The child was very young, and surgery for infantile spasms had not been reported in China. The epilepsy center’s director, Tie Fang, pointed out that in the 1990s, Boston Children’s Hospital, affiliated with Harvard University, had begun treating infantile spasms surgically, and in recent years there have been more and more reports of successful surgeries abroad. After repeated discussions among the Epilepsy Center team, the decision was made to perform the surgery on the child.  After careful surgical preparation, the Epilepsy Center’s surgical team gave the child surgical treatment. Cortical EEG was used to further define the location of the origin of the seizure. The deep lesion in the left temporal lobe of the child was completely excised, and the cortical EEG was reviewed after the lesion was removed to clarify the disappearance of abnormal epileptic discharges. During the operation, the whole surgical team cooperated exceptionally well and did not waste a single moment of precious time, which was entirely due to the detailed preoperative preparation of the surgical team, many simulation rehearsals and the close cooperation of the operating room staff. Everyone wanted to keep the operation time as short as possible in order to reduce the anesthesia time and the impact of the operation on the child.  After the surgery, the child passed through the risky period of surgery with the close cooperation of the surgical team, PICU doctors and neurosurgery staff. On the first day after surgery, the child was able to call out clearly,
The child was able to call “daddy, mommy” clearly and communicate with his family in a simple way. The child was discharged from the hospital on the fifth day after surgery because the surgical team gave the child intracutaneous sutures in the scalp. The postoperative pathology confirmed that the small lesion in the deep brain of the child was cortical dysplasia, specifically typed as FCD type IIA. The family is grateful that the child has not had any more seizures after surgery!