Gallbladder stones are a common disease in biliary surgery. For many years, the medical community has been seeking and exploring safe, effective, less painful, minimally invasive, and more patient-friendly gallstone treatment methods. The widespread use of laparoscopic and cholangioscopic technologies in clinical practice has extended the surgeon’s vision into the gallbladder, and gallstone treatment has begun to enter a new era of safe and effective treatment – the era of laparoscopic minimally invasive biliary stone extraction. Laparoscopic minimally invasive biliary stone extraction is performed by entering the abdominal cavity through a laparoscope and then applying advanced choledochoscopic techniques to remove stones from the gallbladder while preserving the functional gallbladder. Laparoscopic minimally invasive biliary lithotomy not only preserves the gallbladder and its function, but also removes stones and eliminates clinical symptoms, fully embodying the concept of “minimal trauma”. Laparoscopic minimally invasive biliary stone extraction has the following advantages: 1. With the wide field of view of the laparoscope, the abdominal organs can be explored for other lesions, and the feasibility of preserving the gallbladder can be evaluated again under direct vision, and the stones can be removed under direct vision of the cholangioscope, which ensures the net rate of gallstones and stone extraction effect and reduces the recurrence rate; 2. 3. If the gallbladder is not suitable for preservation, laparoscopic cholecystectomy can be performed directly. Minimally invasive laparoscopic cholecystectomy can be considered in the following cases: 1. asymptomatic gallbladder stones, so-called “resting state” of stones, which you want to remove and preserve the gallbladder; 2. the gallbladder must have good contraction function; 3. the gallbladder cannot be too large or too small; 4. the upper abdomen cannot have a history of open surgery, perforation and other acute inflammatory diseases; 5. 5. Under ultrasound, the mucosa of the gallbladder is smooth, the wall of the gallbladder is within 3-4 mm, the stones are single or multiple, the morphology is regular, the sound transmission in the gallbladder is good, the long diameter of the gallbladder is between 5-8 cm, and there can be no separation in the cyst; 6. Although there are no obvious restrictions on age, young people are more suitable. The following conditions are not suitable for minimally invasive laparoscopic cholecystectomy: 1, the gallbladder in the acute inflammatory stage (including suppuration, gangrene, perforation, inflammatory package, gallbladder neck or gallbladder duct stone impaction, etc.); 2, gallbladder stones combined with gallbladder polyps, or sediment-like stones; 3, gallbladder atrophy; 4, gallbladder adenomyosis or gallbladder wall thickening, which cannot exclude gallbladder cancer; 5, the gallbladder has separation, dividing the gallbladder into connected The gallbladder is divided into two cavities. The specific treatment plan for each patient needs to be “individualized” according to the doctor’s opinion in order to get the best treatment effect.