Indications for cholecystectomy 1, no symptoms of gallbladder stones, the so-called stone “resting state”. 2, the gallbladder must have good contraction function: oral cholecystography or ultrasound after lipid meal suggests that the gallbladder is contracted up to 1/3 or more. 3, the gallbladder must not be too large or too small, the gallbladder length diameter is between 6-200px, and there must not be separation within the sac. 4, The upper abdomen should preferably have no history of open surgery, perforation and other acute inflammation history. 5, under ultrasound: good intra-biliary sound transmission, smooth gallbladder mucosa, gallbladder wall within 3-5mm, single or multiple stones (except sediment-like stones), regular morphology, stones can move with changes in vitro. Contraindications for bile stone extraction 1.Gallbladder atrophy, gallbladder wall thickening, disappearance of gallbladder cavity, combined with common bile duct stones. 2.Stones in the gallbladder duct cannot be removed and are expected to remain unremoved after surgery. 3.The gallbladder duct is confirmed to be obstructed by intraoperative angiography. 4.Mirizz syndrome. 5.It is confirmed that the gallbladder has completely lost its function. 6.Stones in the gallbladder duct are seen on intraoperative ultrasonography and cannot be detected by intraoperative choledochoscopy.